Clonal cell line-based, multigene-modified, off-the-shelf NK cell therapeutics are emerging as the new frontier of adoptive cellular immunotherapy.Here, we utilized a newly established NK cell line, NK101, as a backbone to derive multifaceted killer cells armored with various antitumor modalities through repeated cycles of genetic modification and
Background: Low back pain (LBP) is the leading global cause of years lived with disability (YLD), with high body mass index (BMI) recognized as a significant and modifiable risk factor.While prior research has linked high BMI to LBP, comprehensive global assessments of the burden attributable to high BMI are scarce.Methods: We analyzed data from th
Son of Saul, the Hungarian director, László Nemes Jeles’s film about Holocaust was released in 2015 with great international success: Grand Prix of the Airliner Cannes Film Festival, the Academy Award and Golden Globe for best foreign-language film.In my essay, I approach the film from a variety of perspectives.First, by analysing the visual an
All kinds of violence, especially domestic violence, be human rights infringement and crime towards humanity dignity with Steamrollers discrimination form that must be wiped off.Domestic violence often accepted by woman as victim and at the time of same actually they have overrided rights and their autonomy is as individual by family wholeness and